{"id":4378420281457,"title":"Boston Heart HDL Map","handle":"boston-heart-hdl-map","description":"\u003cp\u003e\u003cstrong\u003eAvailable in clinic and online. \u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003eThe Boston Heart HDL Map\u003csup\u003e®\u003c\/sup\u003e is the only test available that quantifies the amount of apoA-I in the five most significant subpopulations, resulting in a deeper understanding of a patient’s CVD risk. 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Because HDL is comprised of subpopulations of different sizes, composition and characteristics that impact cardiovascular risk in drastically different ways\u003cstrong\u003e.\u003c\/strong\u003e Healthcare providers can use this information to determine the most effective treatment strategy, as well as monitor response to therapy.\u003c\/p\u003e\n\n\u003ch4\u003ePreferred Specimen\u003c\/h4\u003e\n\n\u003cp\u003e1.0 mL EDTA plasma (0.5 mL minimum) collected in plasma separator tube (Pearl Top)\u003c\/p\u003e\n\n\u003cp\u003e \u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eSchedule your visit\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003eTo know which diagnostic tests you need, schedule a \u003ca href=\"https:\/\/afhlife.com\/products\/discovery-visit-s0104\"\u003eDiscovery Visit\u003c\/a\u003e and talk with our doctors.\u003c\/p\u003e\n\n\u003cp\u003eTo learn more about your test results, schedule an \u003ca href=\"https:\/\/afhlife.com\/products\/insight-visit-s0105\"\u003eInsight Visit\u003c\/a\u003e and discuss with our doctors.\u003c\/p\u003e\n\n\u003cp\u003eTo convert your diagnostic test result to health actions, schedule an \u003ca href=\"https:\/\/afhlife.com\/products\/action-visit-s0106\"\u003eAction Visit\u003c\/a\u003e and get intelligent lifestyle design and recommendations from our doctors.\u003c\/p\u003e\n\n\u003cp\u003eTo monitor your health journey, schedule a \u003ca href=\"https:\/\/afhlife.com\/products\/monitoring-visit-s0107\"\u003eMonitoring Visit\u003c\/a\u003e to be fully supported on habitual and lifestyle changes.\u003c\/p\u003e\n\n\u003cp\u003e \u003c\/p\u003e\n\n\u003cp\u003ePlease contact us at (714) 864-3730 or pe@anti-fragilityhealth.com to order your test and for more information.\u003c\/p\u003e\n"}

Boston Heart HDL Map

Price: Login to See the Price and Member Discount

$181.00

Available in clinic and online. 

The Boston Heart HDL Map® is the only test available that quantifies the amount of apoA-I in the five most significant subpopulations, resulting in a deeper understanding of a patient’s CVD risk. Because HDL is comprised of subpopulations of different sizes, composition and characteristics that impact cardiovascular risk in drastically different ways. Healthcare providers can use this information to determine the most effective treatment strategy, as well as monitor response to therapy.

Preferred Specimen

1.0 mL EDTA plasma (0.5 mL minimum) collected in plasma separator tube (Pearl Top)

 

Schedule your visit

To know which diagnostic tests you need, schedule a Discovery Visit and talk with our doctors.

To learn more about your test results, schedule an Insight Visit and discuss with our doctors.

To convert your diagnostic test result to health actions, schedule an Action Visit and get intelligent lifestyle design and recommendations from our doctors.

To monitor your health journey, schedule a Monitoring Visit to be fully supported on habitual and lifestyle changes.

 

Please contact us at (714) 864-3730 or pe@anti-fragilityhealth.com to order your test and for more information.

Sku : A2770
Brand : Boston Heart

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Boston Heart HDL Map®

For more than forty years, total circulating HDL cholesterol (HDL-C) has been used as a primary indicator of cardiovascular disease (CVD) risk. However, HDL is comprised of subpopulations of different sizes, composition and characteristics that impact cardiovascular risk in drastically different ways.

Data from the Framingham Heart Study, Framingham Offspring Study, Veterans Affairs HDL Cholesterol Intervention Trial (VA-HIT) and HDL-Atherosclerosis Treatment Study (HATS) have shown that HDL subpopulations are significantly better predictors of CVD risk than HDL-C values alone.

The Boston Heart HDL Map® is the only test available that quantifies the amount of apoA-I in the five most significant subpopulations, resulting in a deeper understanding of a patient’s CVD risk. This exclusive method provides healthcare providers with an accurate and consistent indication of reverse cholesterol transport by separating the larger, cardioprotective particles most associated with decreased CVD risk from the smaller HDL particles associated with increased risk. Healthcare providers can use this information to determine the most effective treatment strategy, as well as monitor response to therapy.

Test Details

The Boston Heart HDL Map® test measures the five most significant HDL subpopulations in CVD risk using a proprietary gel electrophoresis technique. This process quantifies the amount of apoA-I protein in each of the five HDL subclasses, providing information to accurately identify patients at increased CVD risk.

Methodology

Proprietary PAGE system

Patient Preparation

8-12 hour fast prior to collection. Patient may drink water only.

Preferred Specimen

1.0 mL EDTA plasma (0.5 mL minimum) collected in plasma separator tube (Pearl Top)

Transport Temperature

Refrigerated (ship on frozen cold packs)

Stability

Refrigerated:  2 days (sample must be received within 2 days of collection)

 

Lab Values

Male

  Optimal Borderline Increased Risk
    mg/dL  
α-1 >35.0 25.0-35.0 <25.0
α-2 >55.0 45.0-55.0 <45.0
α-3 <20.0 20.0-25.0 >25.0
α-4 <20.0 20.0-25.0 >25.0
Preβ-1 <20.0 20.0-25.0 >25.0

Female

  Optimal Borderline Increased Risk
    mg/dL  
α-1 >45.0 35.0-45.0 <35.0
α-2 >65.0 55.0-65.0 <55.0
α-3 <20.0 20.0-25.0 >25.0
α-4 <20.0 20.0-25.0 >25.0
Preβ-1 <20.0 20.0-25.0 >25.0

 

Clinical Significance

Low α-1 level is a significant predictor of recurrent CVD events1

  • Low levels of α-1 HDL and high levels of pre ß-1 HDL predicted recurrent CVD events versus no recurrence in men selected for low HDL-C (<40 mg/dL) and CVD. Low α-1 HDL levels have been shown to be the most significant parameter predicting CVD recurrence (p<0.001).1

References:

1. Asztalos BF, Cupples LA, Demissie S, Horvath KV, Cox CE, Batista MC, Schaefer EJ. High-density lipoprotein subpopulation profile and coronary heart disease prevalence in male participants in the Framingham Off spring Study. Arterioscler Thromb Vasc Biol. 2004; 24(11):2181-2187.

 

Treatment Options

  • Lifestyle modification (if indicated)
    • Low saturated fat (<7%)
    • Low cholesterol (<200 mg/day)
    • Low sugar
  • Exercise >30 minutes per day
  • Smoking cessation
  • Weight reduction (if indicated)
  • Medications and their impact on HDL Particles

The Boston Heart HDL Map® is the only test available that quantifies the amount of apoA-I in the five most significant subpopulations, resulting in a deeper understanding of a patient’s CVD risk:

  • α-1
  • α-2
  • α-3
  • α-4
  • Preβ-1

Methodology

Proprietary PAGE system

Patient Preparation

8-12 hour fast prior to collection. Patient may drink water only.

Instructions for Specimen Preparation and Handling