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Primocyn Skin Solution 8 oz

Price: Login to See the Price and Member Discount

$50.00
Primocyn Skin and Wound Care with preservatives is designed for debridement of wounds including Stage I-IV pressure ulcers, partial and full-thickness wounds, diabetic foot ulcers, post surgical wounds, first and second degree burns, grafted and donor sites. This recent advance in wound care has demonstrated rapid in solution eradication of MRSA, VRE and other dangerous pathogens with 99.97% kill in just under 30 seconds, yet is safe to use around eyes, ears and mouth.
Sku : C0223

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Primocyn Skin and Wound Care with preservatives is designed for debridement of wounds including Stage I-IV pressure ulcers, partial and full-thickness wounds, diabetic foot ulcers, post surgical wounds, first and second degree burns, grafted and donor sites. This recent advance in wound care has demonstrated rapid in solution eradication of MRSA, VRE and other dangerous pathogens with 99.97% kill in just under 30 seconds, yet is safe to use around eyes, ears and mouth.

 

Potent Antimicrobial

Time Kill Study: In vitro HOCl eradication of pathogens

  • Greater than 99% reduction in killing 23 different microorganisms, including S. aureus and S. aureus-MRSA
  • Time to kill 30 seconds

Name of Organism

Log Reduction

Log Reduction

Percent Reduction

Acinetobacter baumannii

7.0488

30 seconds

99.9999%

Bacteroides fragilis

3.3565

30 seconds

99.9560%

Candida albicans

6.4699

30 seconds

99.9999%

Corynebacterium diphtherieae

5.2778

30 seconds

99.9995%

Clostridium difficile (spores)

4.6085

30 seconds

99.9975%

Enterobacter aerogenes

6.7200

30 seconds

99.9999%

Enterococcus faecalis-VRE MDR

5.6085

30 seconds

99.9998%

Escherichia coli

6.5272

30 seconds

99.9999%

Haemophilus influenzae

5.4107

30 seconds

99.9996%

Klebsiella oxytoca

6.7810

30 seconds

99.9999%

Klebsiella pneumoniae ozaenae

6.8086

30 seconds

99.9999%

Malassezia furfur

5.3953

30 seconds

99.9996%

Micrococcus yunnanensis

5.6137

30 seconds

99.9998%

Propionibacterium acnes

5.2967

30 seconds

99.9995%

Proteus mirabilis

6.7477

30 seconds

99.9999%

Pseudomonas aeruginosa

6.5867

30 seconds

99.9999%

Serratia marcescens

6.5811

30 seconds

99.9999%

Staphylococcus aureus-MRSA

6.7032

30 seconds

99.9999%

Staphylococcus aureus

6.5008

30 seconds

99.9999%

Staphylococcus pyogenes

6.4214

30 seconds

99.9999%

Trichophyton mentagrophytes

4.6752

30 seconds

99.9979%

Trichophyton rubrum

2.5234

30 seconds

99.7004%

Vibrio vulnificus

5.1888

30 seconds

99.9994%

 

Reduction in Pain and Itch

CASE STUDY #1

Open-Label Study

Study Design

  • Open-label, single-arm study over 7 days

Results

  • HOCl rapidly reduces pruritus in mild-to-moderate atopic dermatitis (AD)
    • 50% of patients experienced a reduction by Day 1
    • 85% of patients experienced a reduction by Day 3

CASE STUDY #2

Randomized, Blinded, Controlled Study

Study Design

  • 72-hour study
  • Treated group (n=19): HOCl BID
  • Untreated group (n=10): No treatment

Results

  • Mean pruritus VAS scores between treated and untreated group were significantly different between baseline and 72 hours post application

Anti-Inflammatory Activity

HOCl for Inhibition of Mast Cell Degranulation

  • Prevents allergen- and calcium-induced mast cell degranulation for up to 8 hours after a single exposure in-vitro
  • Reduces wound inflammation that inhibits healing
  • Stabilizes the mast cell membrane to inhibit the cell machinery for granule secretion, while not altering the signal transduction pathways or calcium mobilization
  • Inhibits degranulation stimulated by antigen or calcium ionophore

Biofilm formation is recognized as a serious problem in chronic wound infections. Biofilm characteristics include

  • Complex structure of microorganisms that generate a protective shell, allowing bacteria to collect and proliferate
  • Most microorganisms that form biofilms found growing in microbial infection
  • Adheres to chronic wounds, makes phagocytosis difficult, and increases resistance to antibiotics
  • Inhibits degranulation stimulated by antigen or calcium ionophore

HOCl has antibiofilm activity and actively breaks down biofilm and kills microorganisms within the biofilm.

  • Provides higher levels of oxygen at a wound site after application
  • Elevated blood and oxygen flow increases wound-healing nutrients

Assists Wound Healing

Wound healing involves a complex sequence of events. Fibroblasts are the primary synthetic cells in the repair process of most structural proteins used during tissue reconstruction.

At lower concentrations, the percentage of fibroblast migration exceeded that of the control at 24 hours.

Although fibroblasts have a critical role in wound healing, their proliferation highly relates to keratinocyte proliferation and mediators secreted from keratinocytes.

Similar results were obtained for keratinocyte migration: At lower HOCl concentrations, the percentage of keratinocyte migration exceeded that of the control at 24 hours.

Primocyn has roots in the science of oxidation. By running an electric current through purified water, the water molecules get split into a positively charged hydrogen ion (H+) and negatively charged hydroxide ion. (-OH).

99.97%Oxidized Water

0.003%Hypoclorus Acid (HOCl)

0.023%Sodium Chloride (NaCl)

0.004%Sodium Hypoclorite (NaOCl)

Instructions

  1. Spray Primocyn Eau Divine Liquid directly or apply Primocyn Hydrogel onto the pierced area.
  2. Repeat as many times necessary.